Project

# Title Team Members TA Documents Sponsor
33 Autologous Transcranial Implant for the Delivery of Photodynamic Therapy for Intracranial Brain Tumors
 Brian Diner
Jack Stender
Mohamed Belakhoua
 Sarath Saroj design_document1.pdf
final_paper1.pdf
proposal1.pdf
video
# Autologous Transcranial Implant for the Delivery of Photodynamic Therapy for Intracranial Brain Tumors

Team Members:
- Jack Stender (stender3)
- Mohamed Belakhoua (mab21)
- Brian Diner (bdiner2)

# Problem

Glioblastoma has a very poor prognosis of 12-15 months post-operation. The current standard of treatment is surgical resection, radiation therapy, and chemotherapy. There exists one FDA-approved device on the market that attempts to solve a similar problem - Optune. Other alternatives exist as well but they have low efficacy overall. In recent trials, photodynamic therapy has proven effective in treating cancerous cells though currently it can only be administered mid-surgery while the brain is exposed.

# Solution

To allow for photodynamic therapy to be administered post-operatively, we propose developing a small transcranial implant that would provide the light source for this therapy. Our objective is to create a programmable device that can be implanted through the skull which will provide control over PDT delivery chronically, allowing patients with GBM to be photo-irradiated without re-entering the operating room after their resection is completed. Components of this transcranial implant would include the appropriate light source, a light diffuser, battery, and an on/off mechanism.


# Solution Components

## Light Source / Light Diffuser

- Medical grade titanium socket implant attached to the skull.
- Medical grade resin printed LED diffuser sitting in metal socket. Similar size to an apple watch in all dimensions

## Battery

- Single-use battery - taking cues from pacemaker design

## On/off Mechanism

- RFID or bluetooth code transmission to the microcontroller determines when and how LEDs are on

# Criterion For Success

Create a working prototype of a Photodynamic Therapeutic device. Create a custom PCB for an LED diode array that can be remotely programmed for the duration and intensity of the light. Design and implement a 3D-printed casing in the dimensions of the final product.

Interactive Proximity Donor Wall Illumination

Sungmin Jang, Anita Jung, Zheng Liu

Interactive Proximity Donor Wall Illumination

Featured Project

Team Members:

Anita Jung (anitaj2)

Sungmin Jang (sjang27)

Zheng Liu (zliu93)

Link to the idea: https://courses.engr.illinois.edu/ece445/pace/view-topic.asp?id=27710

Problem:

The Donor Wall on the southwest side of first floor in ECEB is to celebrate and appreciate everyone who helped and donated for ECEB.

However, because of poor lighting and color contrast between the copper and the wall behind, donor names are not noticed as much as they should, especially after sunset.

Solution Overview:

Here is the image of the Donor Wall:

http://buildingcampaign.ece.illinois.edu/files/2014/10/touched-up-Donor-wall-by-kurt-bielema.jpg

We are going to design and implement a dynamic and interactive illuminating system for the Donor Wall by installing LEDs on the background. LEDs can be placed behind the names to softly illuminate each name. LEDs can also fill in the transparent gaps in the “circuit board” to allow for interaction and dynamic animation.

And our project’s system would contain 2 basic modes:

Default mode: When there is nobody near the Donor Wall, the names are softly illuminated from the back of each name block.

Moving mode: When sensors detect any stimulation such as a person walking nearby, the LEDs are controlled to animate “current” or “pulses” flowing through the “circuit board” into name boards.

Depending on the progress of our project, we have some additional modes:

Pressing mode: When someone is physically pressing on a name block, detected by pressure sensors, the LEDs are controlled to

animate scattering of outgoing light, just as if a wave or light is emitted from that name block.

Solution Components:

Sensor Subsystem:

IR sensors (PIR modules or IR LEDs with phototransistor) or ultrasonic sensors to detect presence and proximity of people in front of the Donor Wall.

Pressure sensors to detect if someone is pressing on a block.

Lighting Subsystem:

A lot of LEDs is needed to be installed on the PCBs to be our lighting subsystem. These are hidden as much as possible so that people focus on the names instead of the LEDs.

Controlling Subsystem:

The main part of the system is the controlling unit. We plan to use a microprocessor to process the signal from those sensors and send signal to LEDs. And because the system has different modes, switching between them correctly is also important for the project.

Power Subsystem:

AC (Wall outlet; 120V, 60Hz) to DC (acceptable DC voltage and current applicable for our circuit design) power adapter or possible AC-DC converter circuit

Criterion for success:

Whole system should work correctly in each mode and switch between different modes correctly. The names should be highlighted in a comfortable and aesthetically pleasing way. Our project is acceptable for senior design because it contains both hardware and software parts dealing with signal processing, power, control, and circuit design with sensors.

Project Videos